People

Rimantas Kodzius, Ph.D.

Postdoctoral Fellows

Postdoctoral Researcher

Seed Fund "Envirola" project manager


Currently with Computational Bioscience REsearch Center (CBRC)


Research Interests

My specialty is in molecular and cell biology, genomics and transcriptomics (Omics overall), high-throughput screening, assay parallelization and microfluidics. One of the important tasks is adaptation of microfluidic systems to solve biological problems. This includes material biocompatibility research, development of DNA/ protein, cell-based sensors and signal (DNA by PCR, protein, etc.) amplification systems. Development of novel chemical and biological sensors is an important aspect in my research. One of the objectives is to develop the Lab-On-Chip (LOC) systems suitable for portable Point-of-Care Testing (POCT). The developed assays are patented with further commercialization.

Selected Publications

Author Kodzius has 25 journal publications which have been cited more than 1777 times in Scopus (stand 15th September 2012). A selected list of publications:

 

Carninci, Piero, Albin Sandelin, Boris Lenhard, Shintaro Katayama, Kazuro Shimokawa, Jasmina Ponjavic, Colin A. M. Semple, et al. "Corrigendum: Genome-Wide Analysis of Mammalian Promoter Architecture and Evolution." Nature Genetics 39, no. 9 (2007): 1174-74.

Consortium, The FANTOM, P. Carninci, T. Kasukawa, S. Katayama, J. Gough, M. C. Frith, N. Maeda, et al. "Corrections and Clarifications: The Transcriptional Landscape of the Mammalian Genome." Science 311, no. 5768 (March 24, 2006): 1713.

Crameri, R., and R. Kodzius. "The Powerful Combination of Phage Surface Display of Cdna Libraries and High Throughput Screening." Combinatorial chemistry & high throughput screening 4, no. 2 (Apr 2001): 145-55.

Crameri, R., R. Kodzius, Z. Konthur, H. Lehrach, K. Blaser, and G. Walter. "Tapping Allergen Repertoires by Advanced Cloning Technologies." International archives of allergy and immunology 124, no. 1-3 (Jan-Mar 2001): 43-7.

Forrest, A. R., D. F. Taylor, M. L. Crowe, A. M. Chalk, N. J. Waddell, G. Kolle, G. J. Faulkner, et al. "Genome-Wide Review of Transcriptional Complexity in Mouse Protein Kinases and Phosphatases.". Genome biology 7, no. 1 (2006): R5.

Gong, Xiuqing, Xin Yi, Kang Xiao, Shunbo Li, Rimantas Kodzius, Jianhua Qin, and Weijia Wen. "Wax-Bonding 3d Microfluidic Chips." Lab on a Chip 10, no. 19 (2010): 2622-27.

Karl, Thomas, Kamil Önder, Rimantas Kodzius, Alena Pichová, Herbert Wimmer, A. Thür, Harald Hundsberger, et al. "Grc5 and Nmd3 Function in Translational Control of Gene Expression and Interact Genetically." Current Genetics 34, no. 6 (1999): 419-29.

Kodzius, R., C. Rhyner, Z. Konthur, D. Buczek, H. Lehrach, G. Walter, and R. Crameri. "Rapid Identification of Allergen-Encoding Cdna Clones by Phage Display and High-Density Arrays.". Combinatorial chemistry & high throughput screening 6, no. 2 (Mar 2003): 147-54.

Kodzius, Rimantas, Miki Kojima, Hiromi Nishiyori, Mari Nakamura, Shiro Fukuda, Michihira Tagami, Daisuke Sasaki, et al. "Cage: Cap Analysis of Gene Expression." Nat Meth 3, no. 3 (2006): 211-22.

Kodzius, Rimantas, Yonehiro Matsumura, Takeya Kasukawa, Kazuro Shimokawa, Shiro Fukuda, Toshiyuki Shiraki, Mari Nakamura, et al. "Absolute Expression Values for Mouse Transcripts: Re-Annotation of the Read Expression Database by the Use of Cage and Est Sequence Tags." FEBS Letters 559, no. 1–3 (2004): 22-26.

Kodzius, Rimantas, Kang Xiao, Jinbo Wu, Xin Yi, Xiuqing Gong, Ian G. Foulds, and Weijia Wen. "Inhibitory Effect of Common Microfluidic Materials on Pcr Outcome." Sensors and Actuators B: Chemical 161, no. 1 (2012): 349-58.

Li, Huawei, Yiqiang Fan, Rimantas Kodzius, and Ian G. Foulds. "Fabrication of Polystyrene Microfluidic Devices Using a Pulsed Co2 Laser System." Microsyst. Technol. 18, no. 3 (2012): 373-79.

Rhyner, C., R. Kodzius, and R. Crameri. "Direct Selection of Cdnas from Filamentous Phage Surface Display Libraries: Potential and Limitations." Current pharmaceutical biotechnology 3, no. 1 (Mar 2002): 13-21.

Schaefer, Ulf, Rimantas Kodzius, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, and Vladimir B. Bajic. "High Sensitivity Tss Prediction: Estimates of Locations Where Tss Cannot Occur." PLoS ONE 5, no. 11 (2010): e13934.

Shiraki, Toshiyuki, Shinji Kondo, Shintaro Katayama, Kazunori Waki, Takeya Kasukawa, Hideya Kawaji, Rimantas Kodzius, et al. "Cap Analysis Gene Expression for High-Throughput Analysis of Transcriptional Starting Point and Identification of Promoter Usage." Proceedings of the National Academy of Sciences 100, no. 26 (December 23, 2003 2003): 15776-81.

Tan, Yue Ying, Rimantas Kodzius, Boon-Hui Tay, Alice Tay, Sydney Brenner, and Byrappa Venkatesh. "Sequencing and Analysis of Full-Length Cdnas, 5'-Ests and 3'-Ests from a Cartilaginous Fish, the Elephant Shark (Callorhinchus Milii)." PLoS One (2012 (in press)).

Wang, Jianli, Alison P. Lee, Rimantas Kodzius, Sydney Brenner, and Byrappa Venkatesh. "Large Number of Ultraconserved Elements Were Already Present in the Jawed Vertebrate Ancestor." Molecular Biology and Evolution 26, no. 3 (March 1, 2009 2009): 487-90.

Wang, Limu, Rimantas Kodzius, Xin Yi, Shunbo Li, Yu Sanna Hui, and Weijia Wen. "Prototyping Chips in Minutes: Direct Laser Plotting (Dlp) of Functional Microfluidic Structures." Sensors and Actuators B: Chemical 168, no. 0 (2012): 214-22.

Wu, Jinbo, Rimantas Kodzius, Kang Xiao, Jianhua Qin, and Weijia Wen. "Fast Detection of Genetic Information by an Optimized Pcr in an Interchangeable Chip." Biomedical microdevices 14, no. 1 (2012): 179-86.

Yi, Xin, Rimantas Kodzius, Xiuqing Gong, Kang Xiao, and Weijia Wen. "A Simple Method of Fabricating Mask-Free Microfluidic Devices for Biological Analysis." Biomicrofluidics 4, no. 3 (2010): 036503-8.

Education

From 2010 – Scientific research at KAUST

From 2009 – Training in Joint KAUST-HKUST Micro/ Nanofluidics laboratory in Hong Kong

From 2006 – Genomics laboratory, IMCB, Biopolis Drive (Proteos), Singapore

From 2002 – Genomic Science Center, RIKEN, Japan

From 2000 – PhD work at Swiss Institute of Allergy and Asthma Research (SIAF), Switzerland

From 1997 – PhD work at Max-Planck-Institute for Molecular Genetics (MPIMG) in Berlin, Germany

From 1995 – Master thesis at Paris-Lodron-Universität Salzburg, Austria

From 1992 – Bachelors work at Vilnius University, Lithuania

Scientific and Professional Memberships


Awards

01.09.1992 – 01.10.1995 Scholarship from the University of Vilnius

01.10.1995 – 01.10.1996 Scholarship from the city Salzburg

01.10.1996 Recognition and support from Lithuanian Foundation in USA

01.10.1996 – 28.10.1997 Scholarship from government of Salzburg

01.10.1996 – 28.10.1997 Scholarship from Austrian Academic Exchange Service (OAD)

28.10.1997 Recognition and support from Lithuanian Foundation in USA

28.10.1997 – 28.10.1998 Scholarship from German Academic Exchange Service (DAAD)

28.10.1998 – 27.04.2000 Lithuanian Government fellowship

27.04.2000 – 31.01.2002 Support from Swiss National Science Foundation

01.01.2003 – 01.01.2005 Research grant individual fellowship FP5 INCO2 project from EU to Japan

26.06.2005 – 01.07.2005 Fellowship to participate 55th meeting of Nobel Laureates in Germany

14.01.2012 – 21.01.2012 Cornell University (USA) Entrepreneurship program

14.03.2012 Received $200.000 Seed Funding from KAUST for high-tech start-up company "Envirola", a spin-off from King Abdullah University of Science and Technology

KAUST Affiliations

Computer, Electrical and Mathematical Sciences and Engineering Division

Electrical Engineering program

Non-KAUST Affiliations

Joint KAUST-HKUST Micro/Nano-Fluidics Laboratory Project at the Hong Kong University of Science and Technology (HKUST)